Cardiology 01, ABSTRACTS XVI ALASBIMN CONGRESS. NUCLEAR MEDICINE 1999.

ABSTRACTS XVI ALASBIMN CONGRESS NUCLEAR MEDICINE 1999.

1. CARDIOLOGY

1.1 EVALUATION OF LV FUNCTION ON ACUTE MYOCARDIAL INFARCTION COMPARISON BETWEEN 2 NUCLEAR TECHNIQUES

J. Vitola; L. Maia, T. Hsia, M. Freeman. F. Salis, M. Loyo, A. Joaquim, E. Paiva, C. Meneghetti

Rio Preto Medical School, Sao Paulo University and University of Toronto

Evaluation of left ventricular (LV) function in patients with acute myocardial infarction (AMI) is important for diagnostic and prognostic reasons and helps to guide therapy. Measurements of LV volumes is extremely useful for the follow up of ventricular remodeling AMI. We studied 38 patients in the first 5 days of an anterior AMI, using radionuclide ventriculography. Images were acquired on the best LAO projection. 32 frames/cycle. and a total of 3.2. million counts. Twenty of these patients also underwent blood sampling and additional anterior image with external source for attenuation correction. We applied 2 nuclear techniques to evaluate ventricular function: a relative volume technique (without attenuation correction) and an absolute volume technique (with attenuation correction and blood sampling) Comparison was performed by t-test and linear regression analysis. Values were expressed as mean + SD.A p value of <0.05 was considered significant. EF: ejection fraction. PFR: peak filling rate. EDV: end diastolic volume. ESV: end systolic volume, stroke volume, CO: cardiac output. Results:

	Relative	Absolute	t-test	Correlation
LVEF	45 + 12	28 + 11	0.4	r=0.96
PFR	2.2+ 0.1	2.0+ 0.6	0.4	r=0.89
LVEDV	102 + 30	132 + 54	0.01*	r=0.66
LVESV	56 + 20	82+ 32	0.03*	r=0.53
LVSV	46 + 17	50 + 30	0.01*	r=0.83
CO	3.1 + 1.0	3.5 + 1.7	0.02*	r=0.73

Conclusions:

(1) Ejection fraction and PFR (a parameter of diastolic dysfunction) were depressed by both techniques. which did not differ significantly from each other. There was excellent correlation between techniques.

(2) Measurements of LV volumes and CO differ significantly between techniques. Nevertheless, they correlated reasonably well. Especially for SV and CO measurements, suggesting that either one can be used to evaluate remodeling. (3) The standard deviation of values tended to be smaller for the relative volume technique.

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