Abstracts XIX Brazilian Congress of Nuclear Medicine
9. PET/SPECT
9.4 - [F-18]FDG SCINTIGRAPHY IN ONCOLOGICAL PATIENTS. PRELIMINARY DATA.
Ramos CD, Santos AO, Etchebehere ECSC, Sagarra A, Pizão PE, Lima MCL, Camargo EE. Division of Nuclear Medicine, Department of Radiology, Campinas State University (UNICAMP) and Division of Oncology, Hospital Celso Pierro (PUCC), Campinas, Brazil.
Oncologic studies with [F-18] FDG have been recently further expanded with the new scintillation cameras that perform positron emission images using high energy collimators or coincidence detection. To evaluate the usefulness of [F-18] FDG images acquired on a two-detector scintillation camera equipped with high energy collimators 6 patients (pts) (6 males, 4 females, 25 to 67 years, mean 51.7 yrs) were studied: 2 with adenocarcinoma of the colon, 1 with spindle-cell lung carcinoma, 1 with renal cell carcinoma, 1 with carcinoid tumor and 1 with thymoma. Images were begun 40 to 90 minutes after an intravenous injection of 440 to 740 MBq (12 to 20 mCi) of [F-18] FDG. All pts were in the fasting state for 6 hours and had blood glucose levels below 110 mg% at the time of injection. Whole-body and tomographic images of the thorax and abdomen/pelvis were acquired in all pts. [Tc-99m] sulfur colloid images in 3 pts, [Tc-99m]MDP images in 2 pts and gallium-67 images in 1 pt were acquired simultaneously to the [F-18] FDG images. [F-18] FDG images were compared to computed tomography (CT) and surgical findings in 2 pts, to CT only in 2 pts, to CT and bone scintigraphy in 1 pt, and to octeotride scintigraphy and mammography in 1pt. [F-18]FDG images demonstrated clinically relevant findings in 4 pts and led to a change in pt management. In one pt there was no [F-18] FDG uptake and in another pt it was not possible to distinguish tumor uptake from the physiologic uptake of the radiopharmaceutical in the intestines. [F-18] FDG images acquired in a scintillation camera equipped with high energy collimators are very useful and may change clinical management in a significant number of pts. These systems also allow simultaneous acquisition of images with another radiopharmaceutical thus improving anatomical references and the level of confidence.
1.Cardiology | 2.Endocrinology | 3.Equipment: Quality Control | 4.Gastroenterology | 5.Infectious Diseases | 6.Nephro-Urology | 7.Oncology | 8.Orthopheadics | 9.PET/SPECT | 10.Pneumology | 11.Radiobiology | 12.Radiopharmacy | 13.Special Clinical Applications | 14.Neuropsychiatry |