COMPARATIVE FUNCTIONAL STUDY OF TWO PSYCHIATRIC PATHOLOGIES BY MEANS OF BRAINSPECT TC 99 HMPAO: MAJOR DEPRESSION AND BORDERLINE PERSONALITY DISORDER.

METHOLOGY

Sample

In a population of patients consulting spontaneously, we took a sample of 249 persons who were diagnosed with psychiatric disorders following D.S.M. IV criteria with the objective of comparing blood brain flows in basal conditions versus activation conditions through the Wisconsin test, in the sample of patients with Borderline Personality Disorder as well as patients with Mayor Depression.

The criteria of inclusion were:

To fulfill criteria of D.S.M. IV.

Interview a significant relative concurring with the diagnosis.

Rorschach Test concordant with the referred pathology.

In the case of depressive patients it was required also a score in the Hamilton scale for depression > 24 .

It was found that 49 patients fulfilled criteria of Borderline Personality Disorder, of which 18 had de Neurospect in basal conditions and 31 in stimulation conditions.

It was obtained a group of 40 patients who fulfilled the criteria of Mayor Depressive Disorder, of which 23 had de Neurospect Test in basal conditions and 27 in stimulation conditions.

In both groups the patients consuming psychopharmaceuticals were discarded. In the case of antipsychotic drugs it was indicated at least 15 days of suspension and 2 months if these were of deposit. The antidepressives should be suspended at least 20 days before the Spect. The patients addicted to drugs were excluded.

Both groups are comparable in sex and age as shown in Tables (I and II)

TABLE I

SEX AND AGE COMPARISON.

PATIENTS WITH MAJOR DEPRESSION AND BORDERLINE PERSONALITY DISORDER

DEPRESSION

TABLE II

SEX AND AGE COMPARISON IN BASAL CONDITIONS.

PATIENTS WITH MAJOR DEPRESSION AND BORDERLINE PERSONALITY DISORDER

BASAL

P>0.05 Fisher

P>0.05 Mann – Whitney

SEX AND AGE COMPARISON WISCONSIN TEST.

PATIENTS WITH MAJOR DEPRESSION AND BORDERLINE PERSONALITY DISORDER

WISCONSIN

P>0.05 Fisher

P>0.05 Mann – Whitney

These tables demonstrate that both groups are comparable as per sex and age.

We analyzed also SPECT in Basal condition and during stimulation with Wisconsin Test.

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